教員データベース - 角田　慎一 | 神戸学院大学

ツノダ　シンイチ TSUNODA SHINICHI
角田　慎一

所属

神戸学院大学薬学部薬学科

職種教授

著書・論文歴
2023	論文	Bivalent structure of a TNFR2-selective and agonistic TNF-α mutein Fc-fusion protein enhances the expansion activity of regulatory T cells. Scientific Reports 13,13762 (共著)
2022	論文	タンパク質機能改変技術による2型TNF受容体シグナルのユニーク性の解析と創薬応用薬学雑誌 142,1297-1305頁 (単著)
2021	論文	Characterization of a TNFR2-selective agonistic TNF-α mutant and its derivatives as an optimal regulatory T cell expander. The Journal of Immunology 206 (8),1740-1751頁 (共著)
2020	論文	Structural optimization of a TNFR1-selective antagonistic TNF-α mutant to create new-modality TNF-regulating biologics. Journal of Biological Chemistry 295,9379-9391頁 (共著)
2019	論文	An antisense oligonucleotide targeting SRRM4 is a therapeutic medicine for lung cancer Scientific Reports 9,7618 (共著)
2018	論文	Neutrophil depletion exacerbates plegnancy complications, including placental damage, induced by silica nanoparticles in mice. Frontiers in Immunology 9,1850 (共著)
2017	論文	A trimeric structural fusion of an antagonistic tumor necrosis factor-α mutant enhances molecular stability and enables facile modification. Journal of Biological Chemistry 292,6438-6451頁 (共著)
2015	論文	Aminopeptidase P3, a new member of the TNF-TNFR2 signaling complex, induces phosphorylation of JNK1 and JNK2. Journal of Cell Science 128,656-669頁 (共著)
2015	論文	A novel bispecific antibody against human CD3 and ephrin receptor A10 for breast cancer therapy PLoS One 10,e0144712 (共著)
2013	論文	Robo4 is an effective tumor endothelial marker for antibody-drug conjugates based on the rapid isolation of the anti-Robo4 cell-internalizing antibody. Blood 121,2804-2813頁 (共著)
2010	論文	Solution of the structure of the TNF-TNFR2 complex. Science Signaling 3,ra83 (共著)
2010	論文	The IL-1 family cytokines as mucosal vaccine adjuvant for the induction of protective immunity against influenza virus. Journal of Virology 84,12703-12712頁 (共著)
2016	論文	High-dose cutaneous exposure to mite allergen induces IgG-mediated protection against anaphylaxis. Clinical & Experimental Allergy 46,992 (共著)
2016	論文	Metal nanoparticles in the presence of lipopolysaccharides trigger the onset of metal allergy in mice. Nature Nanotechnology 11,808-816頁 (共著)
2016	論文	Moesin is activated in cardiomyocytes in experimental autoimmune myocarditis and mediates cytoskeletal reorganization with protrusion formation American Journal of Physiology Heart and Circulatory Physiology 311,H476-H486頁 (共著)
2016	論文	The matrix proteins Hasp and Hig exhibit segregated distribution within synaptic clefts and play distinct roles in synaptogenesis The Journal of Neuroscience 36,590-606頁 (共著)
2014	論文	Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers Journal of Controlled Release 189,72-79頁 (共著)
2008	論文	Comparative Study of the Protein Transduction Domains-Mediated Molecular Transduction British Journal of Pharmacology 153,1143-1152頁 (共著)
2008	論文	Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist. Journal of Biological Chemistry (共著)